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Landmark studies on the glucagon subfamily of GPCRs: from small molecule modulators to a crystal structure
The glucagon subfamily of class B G protein-coupled receptors (GPCRs) has been proposed to be a crucial drug target for the tretmaent of type 2 diabetes. The challenges associated with determining the crystal structures of class B GPCRs relate to their large amino termini and the lack of available s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561977/ https://www.ncbi.nlm.nih.gov/pubmed/26279155 http://dx.doi.org/10.1038/aps.2015.78 |