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Fusion Proteins for Half-Life Extension of Biologics as a Strategy to Make Biobetters

The purpose of making a “biobetter” biologic is to improve on the salient characteristics of a known biologic for which there is, minimally, clinical proof of concept or, maximally, marketed product data. There already are several examples in which second-generation or biobetter biologics have been...

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Detalles Bibliográficos
Autor principal: Strohl, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562006/
https://www.ncbi.nlm.nih.gov/pubmed/26177629
http://dx.doi.org/10.1007/s40259-015-0133-6