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Non-CpG Oligonucleotides Exert Adjuvant Effects by Enhancing Cognate B Cell-T Cell Interactions, Leading to B Cell Activation, Differentiation, and Isotype Switching

Natural and synthetic nucleic acids are known to exert immunomodulatory properties. Notably, nucleic acids are known to modulate immune function via several different pathways and various cell types, necessitating a complex interpretation of their effects. In this study we set out to compare the eff...

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Detalles Bibliográficos
Autores principales: Herbáth, Melinda, Papp, Krisztián, Erdei, Anna, Prechl, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562091/
https://www.ncbi.nlm.nih.gov/pubmed/26380319
http://dx.doi.org/10.1155/2015/340468