A novel somatic mutation in ACD induces telomere lengthening and apoptosis resistance in leukemia cells

BACKGROUND: The identification of oncogenic driver mutations has largely relied on the assumption that genes that exhibit more mutations than expected by chance are more likely to play an active role in tumorigenesis. Major cancer sequencing initiatives have therefore focused on recurrent mutations...

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Detalles Bibliográficos
Autores principales: Spinella, Jean-François, Cassart, Pauline, Garnier, Nicolas, Rousseau, Philippe, Drullion, Claire, Richer, Chantal, Ouimet, Manon, Saillour, Virginie, Healy, Jasmine, Autexier, Chantal, Sinnett, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562123/
https://www.ncbi.nlm.nih.gov/pubmed/26345285
http://dx.doi.org/10.1186/s12885-015-1639-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562123/
https://www.ncbi.nlm.nih.gov/pubmed/26345285
http://dx.doi.org/10.1186/s12885-015-1639-5

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