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A novel somatic mutation in ACD induces telomere lengthening and apoptosis resistance in leukemia cells
BACKGROUND: The identification of oncogenic driver mutations has largely relied on the assumption that genes that exhibit more mutations than expected by chance are more likely to play an active role in tumorigenesis. Major cancer sequencing initiatives have therefore focused on recurrent mutations...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562123/ https://www.ncbi.nlm.nih.gov/pubmed/26345285 http://dx.doi.org/10.1186/s12885-015-1639-5 |