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Organ Impairment—Drug–Drug Interaction Database: A Tool for Evaluating the Impact of Renal or Hepatic Impairment and Pharmacologic Inhibition on the Systemic Exposure of Drugs

The organ impairment and drug–drug interaction (OI-DDI) database is the first rigorously assembled database of pharmacokinetic drug exposure data from publicly available renal and hepatic impairment studies presented together with the maximum change in drug exposure from drug interaction inhibition...

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Detalles Bibliográficos
Autores principales: Yeung, CK, Yoshida, K, Kusama, M, Zhang, H, Ragueneau-Majlessi, I, Argon, S, Li, L, Chang, P, Le, CD, Zhao, P, Zhang, L, Sugiyama, Y, Huang, S-M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562165/
https://www.ncbi.nlm.nih.gov/pubmed/26380158
http://dx.doi.org/10.1002/psp4.55