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Organ Impairment—Drug–Drug Interaction Database: A Tool for Evaluating the Impact of Renal or Hepatic Impairment and Pharmacologic Inhibition on the Systemic Exposure of Drugs
The organ impairment and drug–drug interaction (OI-DDI) database is the first rigorously assembled database of pharmacokinetic drug exposure data from publicly available renal and hepatic impairment studies presented together with the maximum change in drug exposure from drug interaction inhibition...
Autores principales: | Yeung, CK, Yoshida, K, Kusama, M, Zhang, H, Ragueneau-Majlessi, I, Argon, S, Li, L, Chang, P, Le, CD, Zhao, P, Zhang, L, Sugiyama, Y, Huang, S-M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562165/ https://www.ncbi.nlm.nih.gov/pubmed/26380158 http://dx.doi.org/10.1002/psp4.55 |
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