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Structural and Thermodynamic Characteristics of Amyloidogenic Intermediates of β-2-Microglobulin
β-2-microglobulin (β2m) self-aggregates to form amyloid fibril in renal patients taking long-term dialysis treatment. Despite the extensive structural and mutation studies carried out so far, the molecular details on the factors that dictate amyloidogenic potential of β2m remain elusive. Here we rep...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562173/ https://www.ncbi.nlm.nih.gov/pubmed/26348154 http://dx.doi.org/10.1038/srep13631 |