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Structural and Thermodynamic Characteristics of Amyloidogenic Intermediates of β-2-Microglobulin

β-2-microglobulin (β2m) self-aggregates to form amyloid fibril in renal patients taking long-term dialysis treatment. Despite the extensive structural and mutation studies carried out so far, the molecular details on the factors that dictate amyloidogenic potential of β2m remain elusive. Here we rep...

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Detalles Bibliográficos
Autores principales: Chong, Song-Ho, Hong, Jooyeon, Lim, Sulgi, Cho, Sunhee, Lee, Jinkeong, Ham, Sihyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562173/
https://www.ncbi.nlm.nih.gov/pubmed/26348154
http://dx.doi.org/10.1038/srep13631

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