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Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis

Oxidative stress plays a critical role in ischemia/reperfusion-injury, atherosclerosis, and aging. It causes cell damage that leads to apoptosis via uncertain mechanisms. Because conditioned medium from cardiac myocytes subjected to hypoxia/reoxygenation induces extensive apoptosis of cardiac myocyt...

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Detalles Bibliográficos
Autores principales: Seko, Yoshinori, Fujimura, Tsutomu, Yao, Takako, Taka, Hikari, Mineki, Reiko, Okumura, Ko, Murayama, Kimie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562266/
https://www.ncbi.nlm.nih.gov/pubmed/26348594
http://dx.doi.org/10.1038/srep13737