Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart

BACKGROUND: Transient early-life perturbations in glucocorticoids (GC) are linked with cardiovascular disease risk in later life. Here the impact of early life manipulations of GC on adult heart structure, function and gene expression were assessed. METHODS AND RESULTS: Zebrafish embryos were incuba...

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Detalles Bibliográficos
Autores principales: Wilson, K.S., Baily, J., Tucker, C.S., Matrone, G., Vass, S., Moran, C., Chapman, K.E., Mullins, J.J., Kenyon, C., Hadoke, P.W.F., Denvir, M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: North Holland Publishing 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562295/
https://www.ncbi.nlm.nih.gov/pubmed/26219824
http://dx.doi.org/10.1016/j.mce.2015.07.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562295/
https://www.ncbi.nlm.nih.gov/pubmed/26219824
http://dx.doi.org/10.1016/j.mce.2015.07.025

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