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The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women

BACKGROUND: Obesity is associated with changes in fat cell gene expression and metabolism. What drives these changes is not well understood. We aimed to explore fat cell epigenetics, i.e., DNA methylation, as one mediator of gene regulation, in obese women. The global DNA methylome for abdominal sub...

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Detalles Bibliográficos
Autores principales: Arner, Peter, Sinha, Indranil, Thorell, Anders, Rydén, Mikael, Dahlman-Wright, Karin, Dahlman, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562340/
https://www.ncbi.nlm.nih.gov/pubmed/26351548
http://dx.doi.org/10.1186/s13148-015-0126-9