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The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women
BACKGROUND: Obesity is associated with changes in fat cell gene expression and metabolism. What drives these changes is not well understood. We aimed to explore fat cell epigenetics, i.e., DNA methylation, as one mediator of gene regulation, in obese women. The global DNA methylome for abdominal sub...
Autores principales: | Arner, Peter, Sinha, Indranil, Thorell, Anders, Rydén, Mikael, Dahlman-Wright, Karin, Dahlman, Ingrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562340/ https://www.ncbi.nlm.nih.gov/pubmed/26351548 http://dx.doi.org/10.1186/s13148-015-0126-9 |
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