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Impaired osteogenesis in Menkes disease-derived induced pluripotent stem cells
INTRODUCTION: Bone abnormalities, one of the primary manifestations of Menkes disease (MD), include a weakened bone matrix and low mineral density. However, the molecular and cellular mechanisms underlying these bone defects are poorly understood. METHODS: We present in vitro modeling for impaired o...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562349/ https://www.ncbi.nlm.nih.gov/pubmed/26347346 http://dx.doi.org/10.1186/s13287-015-0147-5 |