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Feasibility of up-regulating CD4(+)CD25(+) Tregs by IFN-γ in myasthenia gravis patients

BACKGROUND: In myasthenia gravis (MG) patients, the dysfunction of CD4(+)CD25(+) regulatory T cells (CD4(+)CD25(+) Tregs) may be one of the important pathogenesis of MG. Currently, the role of IFN-γ in autoimmune diseases is still controversial and needs further exploration. In this study, whether I...

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Detalles Bibliográficos
Autores principales: Huang, Shuo, Wang, Weizhi, Chi, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562356/
https://www.ncbi.nlm.nih.gov/pubmed/26347149
http://dx.doi.org/10.1186/s12883-015-0419-9