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Active autophagy but not lipophagy in macrophages with defective lipolysis

During autophagy, autophagosomes fuse with lysosomes to degrade damaged organelles and misfolded proteins. Breakdown products are released into the cytosol and contribute to energy and metabolic building block supply, especially during starvation. Lipophagy has been defined as the autophagy-mediated...

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Detalles Bibliográficos
Autores principales: Goeritzer, Madeleine, Vujic, Nemanja, Schlager, Stefanie, Chandak, Prakash G., Korbelius, Melanie, Gottschalk, Benjamin, Leopold, Christina, Obrowsky, Sascha, Rainer, Silvia, Doddapattar, Prakash, Aflaki, Elma, Wegscheider, Martin, Sachdev, Vinay, Graier, Wolfgang F., Kolb, Dagmar, Radovic, Branislav, Kratky, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562370/
https://www.ncbi.nlm.nih.gov/pubmed/26143381
http://dx.doi.org/10.1016/j.bbalip.2015.06.005