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Active autophagy but not lipophagy in macrophages with defective lipolysis
During autophagy, autophagosomes fuse with lysosomes to degrade damaged organelles and misfolded proteins. Breakdown products are released into the cytosol and contribute to energy and metabolic building block supply, especially during starvation. Lipophagy has been defined as the autophagy-mediated...
Autores principales: | Goeritzer, Madeleine, Vujic, Nemanja, Schlager, Stefanie, Chandak, Prakash G., Korbelius, Melanie, Gottschalk, Benjamin, Leopold, Christina, Obrowsky, Sascha, Rainer, Silvia, Doddapattar, Prakash, Aflaki, Elma, Wegscheider, Martin, Sachdev, Vinay, Graier, Wolfgang F., Kolb, Dagmar, Radovic, Branislav, Kratky, Dagmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562370/ https://www.ncbi.nlm.nih.gov/pubmed/26143381 http://dx.doi.org/10.1016/j.bbalip.2015.06.005 |
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