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Stress-response balance drives the evolution of a network module and its host genome
Stress response genes and their regulators form networks that underlie drug resistance. These networks often have an inherent tradeoff: their expression is costly in the absence of stress, but beneficial in stress. They can quickly emerge in the genomes of infectious microbes and cancer cells, prote...
Autores principales: | González, Caleb, Ray, Joe Christian J, Manhart, Michael, Adams, Rhys M, Nevozhay, Dmitry, Morozov, Alexandre V, Balázsi, Gábor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562500/ https://www.ncbi.nlm.nih.gov/pubmed/26324468 http://dx.doi.org/10.15252/msb.20156185 |
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