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Cocaine enhances HIV-1 gp120-induced lymphatic endothelial dysfunction in the lung

Pulmonary complications are common in both AIDS patients and cocaine users. We addressed the cellular and molecular mechanisms by which HIV and cocaine may partner to induce their deleterious effects. Using primary lung lymphatic endothelial cells (L-LECs), we examined how cocaine and HIV-1 gp120, a...

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Detalles Bibliográficos
Autores principales: Zhang, Xuefeng, Jiang, Susan, Yu, Jinlong, Kuzontkoski, Paula M, Groopman, Jerome E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562568/
https://www.ncbi.nlm.nih.gov/pubmed/26311830
http://dx.doi.org/10.14814/phy2.12482