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Stretch-induced increase in cardiac contractility is independent of myocyte Ca(2+) while block of stretch channels by streptomycin improves contractility after ischemic stunning
Stretching the cardiac left ventricle (LV) enhances contractility but its effect on myoplasmic [Ca(2+)] is controversial. We measured LV pressure (LVP) and [Ca(2+)] as a function of intra-LV stretch in guinea pig intact hearts before and after 15 min global stunning ± perfusion with streptomycin (ST...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562572/ https://www.ncbi.nlm.nih.gov/pubmed/26290532 http://dx.doi.org/10.14814/phy2.12486 |