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Diet-induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload

Heart failure (HF) is the end stage of cardiovascular disease, in which hypertrophic remodeling no longer meets cardiac output demand. Established animal models of HF have provided insights into disease pathogenesis. However, these models are developed on dissimilar metabolic backgrounds from humans...

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Detalles Bibliográficos
Autores principales: Holzem, Katherine M, Marmerstein, Joseph T, Madden, Eli J, Efimov, Igor R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562575/
https://www.ncbi.nlm.nih.gov/pubmed/26290533
http://dx.doi.org/10.14814/phy2.12489