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Regulation of gastric epithelial cell homeostasis by gastrin and bone morphogenetic protein signaling

We reported that transgenic expression of the bone morphogenetic protein (BMP) signaling inhibitor noggin in the mouse stomach, leads to parietal-cell (PC) loss, expansion of transitional cells expressing markers of both mucus neck and zymogenic lineages, and to activation of proliferative mechanism...

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Detalles Bibliográficos
Autores principales: Todisco, Andrea, Mao, Maria, Keeley, Theresa M, Ye, Wei, Samuelson, Linda C, Eaton, Kathryn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562585/
https://www.ncbi.nlm.nih.gov/pubmed/26290525
http://dx.doi.org/10.14814/phy2.12501