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Potentiation of cGMP signaling increases oxygen delivery and oxidative metabolism in contracting skeletal muscle of older but not young humans

Aging is associated with progressive loss of cardiovascular and skeletal muscle function. The impairment in physical capacity with advancing age could be related to an insufficient peripheral O(2) delivery to the exercising muscles. Furthermore, the mechanisms underlying an impaired blood flow regul...

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Detalles Bibliográficos
Autores principales: Nyberg, Michael, Piil, Peter, Egelund, Jon, Sprague, Randy S, Mortensen, Stefan P, Hellsten, Ylva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562591/
https://www.ncbi.nlm.nih.gov/pubmed/26272735
http://dx.doi.org/10.14814/phy2.12508