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BRAF Mutation in Colorectal Cancer: An Update

Colorectal cancer (CRC) is still one of the deadliest cancer-related diseases. About 10% of CRC patients are characterized by a mutation in the B-Raf proto-oncogene serine/threonine kinase (BRAF) gene resulting in a valine-to-glutamate change at the residue 600 (V600E). This mutation is also present...

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Detalles Bibliográficos
Autor principal: Barras, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562608/
https://www.ncbi.nlm.nih.gov/pubmed/26396549
http://dx.doi.org/10.4137/BIC.S25248