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Using Protein Dimers to Maximize the Protein Hybridization Efficiency with Multisite DNA Origami Scaffolds

DNA origami provides a versatile platform for conducting ‘architecture-function’ analysis to determine how the nanoscale organization of multiple copies of a protein component within a multi-protein machine affects its overall function. Such analysis requires that the copy number of protein molecule...

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Detalles Bibliográficos
Autores principales: Verma, Vikash, Mallik, Leena, Hariadi, Rizal F., Sivaramakrishnan, Sivaraj, Skiniotis, Georgios, Joglekar, Ajit P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562706/
https://www.ncbi.nlm.nih.gov/pubmed/26348722
http://dx.doi.org/10.1371/journal.pone.0137125