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Using Protein Dimers to Maximize the Protein Hybridization Efficiency with Multisite DNA Origami Scaffolds
DNA origami provides a versatile platform for conducting ‘architecture-function’ analysis to determine how the nanoscale organization of multiple copies of a protein component within a multi-protein machine affects its overall function. Such analysis requires that the copy number of protein molecule...
Autores principales: | Verma, Vikash, Mallik, Leena, Hariadi, Rizal F., Sivaramakrishnan, Sivaraj, Skiniotis, Georgios, Joglekar, Ajit P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562706/ https://www.ncbi.nlm.nih.gov/pubmed/26348722 http://dx.doi.org/10.1371/journal.pone.0137125 |
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