Identification of Four Mouse Diabetes Candidate Genes Altering β-Cell Proliferation

Beta-cell apoptosis and failure to induce beta-cell regeneration are hallmarks of type 2-like diabetes in mouse models. Here we show that islets from obese, diabetes-susceptible New Zealand Obese (NZO) mice, in contrast to diabetes-resistant C57BL/6J (B6)-ob/ob mice, do not proliferate in response t...

Descripción completa

Detalles Bibliográficos
Autores principales: Kluth, Oliver, Matzke, Daniela, Kamitz, Anne, Jähnert, Markus, Vogel, Heike, Scherneck, Stephan, Schulze, Matthias, Staiger, Harald, Machicao, Fausto, Häring, Hans-Ulrich, Joost, Hans-Georg, Schürmann, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562707/
https://www.ncbi.nlm.nih.gov/pubmed/26348837
http://dx.doi.org/10.1371/journal.pgen.1005506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562707/
https://www.ncbi.nlm.nih.gov/pubmed/26348837
http://dx.doi.org/10.1371/journal.pgen.1005506

Ejemplares similares