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The role of SDF-1/CXCR4 in the vasculogenesis and remodeling of cerebral arteriovenous malformation

BACKGROUND: Cerebral arteriovenous malformation (AVM) involves the vasculogenesis of cerebral blood vessels and can cause severe intracranial hemorrhage. Stromal cell-derived factor-1 (SDF-1) and its receptor, CXCR4, are believed to exert multiple physiological functions including angiogenesis. Thus...

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Detalles Bibliográficos
Autores principales: Wang, Lingyan, Guo, Shaolei, Zhang, Nu, Tao, Yuqian, Zhang, Heng, Qi, Tiewei, Liang, Feng, Huang, Zhengsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562729/
https://www.ncbi.nlm.nih.gov/pubmed/26366086
http://dx.doi.org/10.2147/TCRM.S87590