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Clinical Significance of IGFBP-3 Methylation in Patients with Early Stage Gastric Cancer()

BACKGROUND: IGFBP-3 is a multifunctional protein that inhibits growth and induces apoptosis of cancer cells. Hypermethylation of the promoter represses expression of the IGFBP-3 gene. We undertook this study to assess the impact of IGFBP-3 methylation on survival of early stage gastric cancer patien...

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Detalles Bibliográficos
Autores principales: Kim, Seung Tae, Jang, Hye-Lim, Lee, Jeeyun, Park, Se Hoon, Park, Young Suk, Lim, Ho Yeong, Choi, Min Gew, Bae, Jae Moon, Sohn, Tae Sung, Noh, Jae Hyung, Kim, Sung, Kim, Kyoung-Mee, Kang, Won Ki, Park, Joon Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562974/
https://www.ncbi.nlm.nih.gov/pubmed/26310375
http://dx.doi.org/10.1016/j.tranon.2015.06.001