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Clinical Significance of IGFBP-3 Methylation in Patients with Early Stage Gastric Cancer()
BACKGROUND: IGFBP-3 is a multifunctional protein that inhibits growth and induces apoptosis of cancer cells. Hypermethylation of the promoter represses expression of the IGFBP-3 gene. We undertook this study to assess the impact of IGFBP-3 methylation on survival of early stage gastric cancer patien...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562974/ https://www.ncbi.nlm.nih.gov/pubmed/26310375 http://dx.doi.org/10.1016/j.tranon.2015.06.001 |