Dasatinib Modulates Invasive and Migratory Properties of Canine Osteosarcoma and has Therapeutic Potential in Affected Dogs

BACKGROUND: This investigation sought to elucidate the relationship between hepatocyte growth factor (HGF)–induced metastatic behavior and the tyrosine kinase inhibitors (TKIs) crizotinib and dasatinib in canine osteosarcoma (OS). Preliminary evidence of an apparent clinical benefit from adjuvant th...

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Detalles Bibliográficos
Autores principales: Marley, Kevin, Gullaba, Justine, Seguin, Bernard, Gelberg, Howard B., Helfand, Stuart C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562978/
https://www.ncbi.nlm.nih.gov/pubmed/26310368
http://dx.doi.org/10.1016/j.tranon.2015.03.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562978/
https://www.ncbi.nlm.nih.gov/pubmed/26310368
http://dx.doi.org/10.1016/j.tranon.2015.03.006

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