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Molecular dynamics study on protein–water interplay in the mechanogating of the bacterial mechanosensitive channel MscL

One of the goals of mechanosensitive channel (MSC) studies is to understand the underlying molecular and biophysical mechanisms of the mechano-gating process from force sensing to gate opening. We focus on the latter process and investigate the role of water in the bacterial MSC MscL, which is activ...

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Detalles Bibliográficos
Autores principales: Sawada, Yasuyuki, Sokabe, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562998/
https://www.ncbi.nlm.nih.gov/pubmed/26233760
http://dx.doi.org/10.1007/s00249-015-1065-2