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Pannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes
OBJECTIVE: Defective glucose uptake in adipocytes leads to impaired metabolic homeostasis and insulin resistance, hallmarks of type 2 diabetes. Extracellular ATP-derived nucleotides and nucleosides are important regulators of adipocyte function, but the pathway for controlled ATP release from adipoc...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563021/ https://www.ncbi.nlm.nih.gov/pubmed/26413467 http://dx.doi.org/10.1016/j.molmet.2015.06.009 |