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Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools
BACKGROUND: Diabetes and metabolic syndromes are chronic, devastating diseases with increasing prevalence. Human pluripotent stem cells are gaining popularity in their usage for human in vitro disease modeling. With recent rapid advances in genome editing tools, these cells can now be genetically ma...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563028/ https://www.ncbi.nlm.nih.gov/pubmed/26413465 http://dx.doi.org/10.1016/j.molmet.2015.06.006 |