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Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools

BACKGROUND: Diabetes and metabolic syndromes are chronic, devastating diseases with increasing prevalence. Human pluripotent stem cells are gaining popularity in their usage for human in vitro disease modeling. With recent rapid advances in genome editing tools, these cells can now be genetically ma...

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Detalles Bibliográficos
Autores principales:	Teo, Adrian Kee Keong, Gupta, Manoj K., Doria, Alessandro, Kulkarni, Rohit N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Minireview
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563028/ https://www.ncbi.nlm.nih.gov/pubmed/26413465 http://dx.doi.org/10.1016/j.molmet.2015.06.006

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