Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells

AIMS/HYPOTHESIS: The adipose tissue-derived hormone leptin plays an important role in the maintenance of body weight and glucose homeostasis. Leptin mediates its effects by interaction with leptin receptors (LepRb), which are highly expressed in the hypothalamus and other brain centres, and at lower...

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Detalles Bibliográficos
Autores principales: Soedling, Helen, Hodson, David J., Adrianssens, Alice E., Gribble, Fiona M., Reimann, Frank, Trapp, Stefan, Rutter, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563029/
https://www.ncbi.nlm.nih.gov/pubmed/26413468
http://dx.doi.org/10.1016/j.molmet.2015.06.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563029/
https://www.ncbi.nlm.nih.gov/pubmed/26413468
http://dx.doi.org/10.1016/j.molmet.2015.06.007

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