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Trastuzumab Induces an Immediate, Transient Volume Increase in Humans: A Randomised Placebo-Controlled Trial

BACKGROUND: The exact extent of and the mechanism by which trastuzumab causes cardiac side effects are not completely unravelled. We investigated the (cardiotoxic) side effects of trastuzumab in a relatively large homogeneous population. METHODS: Healthy male volunteers (n = 54) with a left ventricl...

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Detalles Bibliográficos
Autores principales: Reijers, Joannes A.A., Burggraaf, Jacobus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563119/
https://www.ncbi.nlm.nih.gov/pubmed/26425703
http://dx.doi.org/10.1016/j.ebiom.2015.05.002