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Reverse Engineering of Vaccine Antigens Using High Throughput Sequencing-enhanced mRNA Display

Vaccine reverse engineering is emerging as an important approach to vaccine antigen identification, recently focusing mainly on structural characterization of interactions between neutralizing monoclonal antibodies (mAbs) and antigens. Using mAbs that bind unknown antigen structures, we sought to pr...

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Detalles Bibliográficos
Autores principales: Guo, Nini, Duan, Hongying, Kachko, Alla, Krause, Benjamin W., Major, Marian E., Krause, Philip R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563141/
https://www.ncbi.nlm.nih.gov/pubmed/26425692
http://dx.doi.org/10.1016/j.ebiom.2015.06.021