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Comparison of digital PCR platforms and semi-nested qPCR as a tool to determine the size of the HIV reservoir
HIV persists in latently infected cells of patients on antiretroviral therapy (ART). This persistent proviral DNA reservoir is an important predictor of viral rebound upon therapy failure or interruption and forms a major obstacle towards cure. Accurate quantification of the low levels of persisting...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563360/ https://www.ncbi.nlm.nih.gov/pubmed/26350506 http://dx.doi.org/10.1038/srep13811 |