Comparison of digital PCR platforms and semi-nested qPCR as a tool to determine the size of the HIV reservoir

HIV persists in latently infected cells of patients on antiretroviral therapy (ART). This persistent proviral DNA reservoir is an important predictor of viral rebound upon therapy failure or interruption and forms a major obstacle towards cure. Accurate quantification of the low levels of persisting...

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Detalles Bibliográficos
Autores principales: Bosman, K. J., Nijhuis, M., van Ham, P. M., Wensing, A. M. J., Vervisch, K., Vandekerckhove, L., De Spiegelaere, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563360/
https://www.ncbi.nlm.nih.gov/pubmed/26350506
http://dx.doi.org/10.1038/srep13811

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