BACOM2.0 facilitates absolute normalization and quantification of somatic copy number alterations in heterogeneous tumor

Most published copy number datasets on solid tumors were obtained from specimens comprised of mixed cell populations, for which the varying tumor-stroma proportions are unknown or unreported. The inability to correct for signal mixing represents a major limitation on the use of these datasets for su...

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Detalles Bibliográficos
Autores principales: Fu, Yi, Yu, Guoqiang, Levine, Douglas A., Wang, Niya, Shih, Ie-Ming, Zhang, Zhen, Clarke, Robert, Wang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563570/
https://www.ncbi.nlm.nih.gov/pubmed/26350498
http://dx.doi.org/10.1038/srep13955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563570/
https://www.ncbi.nlm.nih.gov/pubmed/26350498
http://dx.doi.org/10.1038/srep13955

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