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The CB(1) cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway
The CB(1) cannabinoid receptor, the main molecular target of endocannabinoids and cannabis active components, is the most abundant G protein-coupled receptor in the mammalian brain. In particular, the CB(1) receptor is highly expressed in the basal ganglia, mostly on terminals of medium-sized spiny...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563779/ https://www.ncbi.nlm.nih.gov/pubmed/25698444 http://dx.doi.org/10.1038/cdd.2015.11 |