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Electrophysiological evidence for voltage-gated calcium channel 2 (Ca(v)2) modulation of mechano- and thermosensitive spinal neuronal responses in a rat model of osteoarthritis
Osteoarthritis (OA) remains one of the greatest healthcare burdens in western society, with chronic debilitating pain-dominating clinical presentation yet therapeutic strategies are inadequate in many patients. Development of better analgesics is contingent on improved understanding of the molecular...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564012/ https://www.ncbi.nlm.nih.gov/pubmed/26247695 http://dx.doi.org/10.1016/j.neuroscience.2015.07.073 |