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1α,25-Dihydroxyvitamin D(3) prevents the differentiation of human lung fibroblasts via microRNA-27b targeting the vitamin D receptor
Pulmonary fibroblasts have key roles in the formation and maintenance of lung structure and function, and are involved in tissue repair and remodeling. Transforming growth factor-β1 (TGF-β1) induces differentiation of fibroblasts into myofibroblasts, the key effector cells in fibrotic states, which...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564074/ https://www.ncbi.nlm.nih.gov/pubmed/26311239 http://dx.doi.org/10.3892/ijmm.2015.2318 |