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HIF1α-Induced by Lysophosphatidic Acid Is Stabilized via Interaction with MIF and CSN5

Macrophage migration inhibitory factor (MIF) is a cytokine that has broad effects on immune system and inflammatory response. A growing body of evidence implicates the role of MIF in tumor growth and metastasis. Lysophosphatidic acid (LPA), a bioactive lipid mediator, regulates colon cancer cell pro...

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Detalles Bibliográficos
Autores principales: No, Yi Ran, Lee, Sei-Jung, Kumar, Ajay, Yun, C. Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564097/
https://www.ncbi.nlm.nih.gov/pubmed/26352431
http://dx.doi.org/10.1371/journal.pone.0137513