Hybridization Properties of RNA Containing 8-Methoxyguanosine and 8-Benzyloxyguanosine

Modified nucleobase analogues can serve as powerful tools for changing physicochemical and biological properties of DNA or RNA. Guanosine derivatives containing bulky substituents at 8 position are known to adopt syn conformation of N-glycoside bond. On the contrary, in RNA the anti conformation is...

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Detalles Bibliográficos
Autores principales: Baranowski, Daniel Sylwester, Kotkowiak, Weronika, Kierzek, Ryszard, Pasternak, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564172/
https://www.ncbi.nlm.nih.gov/pubmed/26353054
http://dx.doi.org/10.1371/journal.pone.0137674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564172/
https://www.ncbi.nlm.nih.gov/pubmed/26353054
http://dx.doi.org/10.1371/journal.pone.0137674

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