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Hybridization Properties of RNA Containing 8-Methoxyguanosine and 8-Benzyloxyguanosine
Modified nucleobase analogues can serve as powerful tools for changing physicochemical and biological properties of DNA or RNA. Guanosine derivatives containing bulky substituents at 8 position are known to adopt syn conformation of N-glycoside bond. On the contrary, in RNA the anti conformation is...
Autores principales: | Baranowski, Daniel Sylwester, Kotkowiak, Weronika, Kierzek, Ryszard, Pasternak, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564172/ https://www.ncbi.nlm.nih.gov/pubmed/26353054 http://dx.doi.org/10.1371/journal.pone.0137674 |
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