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Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif

The corticotropin-releasing hormone receptor type 1 (CRHR1) plays an important role in orchestrating neuroendocrine, behavioral, and autonomic responses to stress. To identify molecules capable of directly modulating CRHR1 signaling, we performed a yeast-two-hybrid screen using the C-terminal intrac...

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Detalles Bibliográficos
Autores principales: Bender, Julia, Engeholm, Maik, Ederer, Marion S., Breu, Johannes, Møller, Thor C., Michalakis, Stylianos, Rasko, Tamas, Wanker, Erich E., Biel, Martin, Martinez, Karen L., Wurst, Wolfgang, Deussing, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564177/
https://www.ncbi.nlm.nih.gov/pubmed/26352593
http://dx.doi.org/10.1371/journal.pone.0136768