KML001 Induces Apoptosis and Autophagic Cell Death in Prostate Cancer Cells via Oxidative Stress Pathway

We investigated the effects of KML001 (NaAsO(2), sodium metaarsenite, Kominox), an orally bioavailable arsenic compound, on the growth and death of human prostate cancer cells and its mechanism of action. Growth inhibition was assessed by cytotoxicity assays in the presence or absence of inhibitor o...

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Detalles Bibliográficos
Autores principales: You, Dalsan, Kim, Yunlim, Jang, Myoung Jin, Lee, Chunwoo, Jeong, In Gab, Cho, Yong Mee, Hwang, Jung Jin, Hong, Jun Hyuk, Ahn, Hanjong, Kim, Choung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564181/
https://www.ncbi.nlm.nih.gov/pubmed/26352139
http://dx.doi.org/10.1371/journal.pone.0137589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564181/
https://www.ncbi.nlm.nih.gov/pubmed/26352139
http://dx.doi.org/10.1371/journal.pone.0137589

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