Atrial SERCA2a Overexpression Has No Affect on Cardiac Alternans but Promotes Arrhythmogenic SR Ca(2+) Triggers

BACKGROUND: Atrial fibrillation (AF) is the most common arrhythmia in humans, yet; treatment has remained sub-optimal due to poor understanding of the underlying mechanisms. Cardiac alternans precede AF episodes, suggesting an important arrhythmia substrate. Recently, we demonstrated ventricular SER...

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Detalles Bibliográficos
Autores principales: Nassal, Michelle M. J., Wan, Xiaoping, Laurita, Kenneth R., Cutler, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564245/
https://www.ncbi.nlm.nih.gov/pubmed/26352986
http://dx.doi.org/10.1371/journal.pone.0137359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564245/
https://www.ncbi.nlm.nih.gov/pubmed/26352986
http://dx.doi.org/10.1371/journal.pone.0137359

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