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Genetic Polymorphisms of IL28B and PNPLA3 Are Predictive for HCV Related Rapid Fibrosis Progression and Identify Patients Who Require Urgent Antiviral Treatment with New Regimens

The assessment of individual risk of fibrosis progression in patients with chronic hepatitis C is an unmet clinical need. Recent genome-wide association studies have highlighted several genetic alterations as predictive risk factors of rapid fibrosis progression in chronic hepatitis C. However, most...

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Detalles Bibliográficos
Autores principales: Tamaki, Nobuharu, Kurosaki, Masayuki, Higuchi, Mayu, Takada, Hitomi, Nakakuki, Natsuko, Yasui, Yutaka, Suzuki, Shoko, Tsuchiya, Kaoru, Nakanishi, Hiroyuki, Itakura, Jun, Takahashi, Yuka, Ogawa, Shintaro, Tanaka, Yasuhito, Asahina, Yasuhiro, Izumi, Namiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564246/
https://www.ncbi.nlm.nih.gov/pubmed/26352693
http://dx.doi.org/10.1371/journal.pone.0137351